Ubiquinol is the reduced form of Coenzyme Q10. Researches have shown that Ubiquinol is useful to the cardiovascular system, helps support arterial health, and promotes optimial heart health. Ideal blood levels for those afflicted with congestive heart failure are considered to be greater than 3.5 micrograms per milliliter. A clinical trial demonstrated that supplementation with only 150 mg per day (within 28 days) of ubiquinol resulted in CoQ10 blood levels of 3.84 mcg/mL. In study participants who took 300 mg per day of ubiquinol, blood CoQ10 levels reached 7.28 mcg/mL.
Coenzyme Q10 and Heart Diseases
CHF (congestive heart failure) means the heart cannot pump enough blood to keep up with the body’s needs. The most common variety of Congestive heart failure, involves weakening of the muscle in the heart’s left ventricle following bouts of ischemia and/or infarction. Coenzyme Q10 levels are decreased in the heart muscle of individuals with heart failure, with the deficiency becoming more pronounced as heart failure severity worsens. Being at the core of cellular energy processes it assumes significance in cells with high energy requirements like the cardiac cells which are extremely sensitive to Coenzyme Q10 de?ciency produced by cardiac diseases. Coenzyme Q10 has therefore, a potential role for prevention and therapy of heart ailments by improving cellular bioenergetics.
When started within 72 hours of myocardial infarction and taken for one year, CoQ10 appears to significantly lower the risk of heart-related events including non-fatal myocardialinfarction. Ubiquinol were associated with improvements in the capability of the heart to pump blood, as well as general heart health scores, according to results reported in the “American Journal of Clinical Nutrition“. In people with chronic heart failure 300 mg of Coenzyme Q10 per day was able to strengthen the heart over a four week period, as did exercise. Coenzyme Q10 levels in the blood were elevated 4 times higher from the supplements, compared to the control group, and even higher when Coenzyme Q10 was combined with exercise. The ejection fraction is an substantial measurement in determining how well your heart is pumping out blood and in diagnosing and tracking heart failure. Healthy individuals have an ejection fraction of 50-75%, while those with CHF (congestive heart failure) usually have values below 20-30%. In a study performed by Dr. Peter Langsjoen, the ejection fraction improved from 24% up to 45% in ubiquinol-treated patients who had follow-up echocardiograms.
In a clinical study of patients with congestive heart failure were given 580 mg per day of ubiquinone. These individuals found increases in blood levels of CoQ10 levels, along with important developments in the ejection fraction of the heart and improvement of the left ventricle, the part of the heart that sends blood out to the body. In other, randomized placebo controlled, double-blind study, 641 people with more severe congestive heart failure were given either a placebo or 150 mg/day of Coenzyme Q10 for one year. The number of patients requiring hospitalization because of worsening failure was 38 percent less in the Coenzyme Q10 group. Coenzyme Q10 cuts mortality by half in people with heart failure, scientists from Denmark reported at the annual meeting of the Heart Failure Association of the European Society of Cardiology, which took place in Lisbon. Coenzyme Q10 is the first drug to improve survival in chronic heart failure since ACE inhibitors and beta blockers more than a decade ago and should be added to standard heart failure treatment, according to lead author Professor Svend Aage Mortensen.