Selenium, an essential  trace mineral, is an critical component of antioxidant systems such as glutathione peroxidase that neutralize and protect against harm caused by free radicals and reactive oxygen species. Without selenium, certain enzymes in body cannot function, disrupting significant physiological reactions.

Selenium Facts

This mineral is needed for the production of selenoproteins, which are enzymes that work as antioxidants that protect the cells in body from free radical damage. Free radicals can damage cell membranes and DNA, and may contribute to aging and a number of conditions, including cancer and heart disease. Antioxidants can neutralize free radicals and may reduce or even help prevent some of the damage they cause. Selenium is incorporated into proteins to make selenoproteins, which are significant antioxidant enzymes. The antioxidant effects of selenoproteins help prevent cellular damage from free radicals.

Glutathione is an antioxidant that the body produces naturally. One of the body’s most important antioxidant enzymes, glutathione peroxidase is used in the liver to detoxify a wide range of potentially harmful molecules. Selenium is a vital component of the antioxidant enzyme known as glutathione peroxidase. Production of glutathione peroxidase for free radical scavenging depends upon the availability of selenium. Selenium and vitamin E have complementary however independent effects as antioxiadants in the protection of cells against the damaging effects of lipid peroxides and free radicals produced during normal metabolism. Vitamin E and selenium work synergistically. Sulforaphane and selenium have also been shown to work synergistically protecting the body cells against damage caused by free radicals. That is, although both selenium and sulforaphane have beneficial effects alone, when they are combined it is reported that their cancer fighting properties are increased thirteen fold.

Selenium Thyroid Function

Selenium is a important mineral for maintaining healthy function of the thyroid gland. Is a necessary component of three enzymes that contribute to thyroid hormone production and your thyroid contains more selenium than any other tissue in your body. (Selenium is needed in the conversion of the thyroid hormone T4 into its active version, T3). One study found that selenium supplementation had a important impact on inflammatory efficiency in thyroid-specific autoimmune disease, and reducing inflammation may limit damage to thyroid tissue.In another study, followed patients for nine months, and found that selenium supplementation reduced thyroid peroxidase antibody levels in the blood, even in selenium sufficient patients. Selenium is also essential for the conversion of T4 to T3, as deiodinase enzymes are selenium-dependent. T3 is the active form of thyroid hormone, and low T3 can cause hypothyroid symptoms. In cases of intense selenium deficiency, conversion of T4 to T3 may be impaired,  prime to hypothyroid symptoms.

Immune System

Selenium is vital in strengthening the body’s immune system. Selenium stimulates the function and development of all types of white blood cells and enhances the ability of lymphocytes and NK cells,  to activate and respond to invaders such as bacteria and viruses, including the flu. Protects your body after a vaccination by making antibodies that fight infections. According to the University of Oregon State this mineral regulates the action of signal molecules, yclept cytokines, which mediate your immune response. Selenium has been noted to have a important influence on both types of immunity. B and T-lymphocytes are the considerable cells responsible for the immune functions. A deficiency of this mineral was associated with decreased production and the spread of these lymphocytes across the body. Selenium, may  help to improve well-being and might  reduce the viral load in HIV-infected patients. Selenium supplementation was found to reduce the viral load in people infected with (HIV) . Experts at the University of Miami discovered that HIV patients taking 200 mcg (micrograms) of selenium daily for 9 months experienced decreases in HIV viral load and improvements in CD4 count compared with those who had a placebo. (January 2007 – Annals of Internal Medicine)

Anti-Cancer Effects

Selenium has many anti-cancer effects, with effects on oxidative stress, DNA methylation and repair, inflammation, cell apoptosis and proliferation, carcinogen detoxification, hormone production, angiogenesis, and immune system. Observational studies indicate that death from cancer, including , colorectal, prostate and lung cancers, is lower among people with higher blood levels or intake of selenium. A study published in the “American Journal of Epidemiology” measured serum selenium levels in over 9,000 Finns from 1968 to 1976. The research in question; revealed that those who previously had serum selenium amounts of less than 46 ng/ml were more likely to get lung cancer.

In one study of 1,312 people, those who took 200 mcg of selenium as selenized yeast per day had 2/3 lower risk of developing prostate cancer throughout the 4.5-year study compared to those who took a placebo. Study results published in 2004 in the Journal of the National Cancer Institute found that people with the highest blood levels of selenium had a 34 % lower risk of abnormal cell growth and developing new polyps in the rectum and colon. A study conducted at “Harvard University“; found that men with high selenium levels have a 65 % lower chance of getting prostate cancer and recommends 159 micrograms of the mineral for the protective effect. Anticancer mechanism; 1-As anti-oxidant, can help protect the body from harmful effects of free radicals. 2- improving immune system function. 3-increasing the levels of selenium metabolites that inhibit tumor cell growth. 4-Affecting the metabolism of carcinogens. 5- Selenium has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis.

Selenium Benefits Fertility

Selenium boosts fertility in men by increasing sperm production. Blood selenium amounts have been found to be lower in men with low sperm counts. Selenoproteins enhance male fertility by increasing sperm count and protecting sperms from oxidative harm. A young and healthy man produces more than four million sperm per hour in each testicle. Selenium acts to help prevent oxidation of the sperm cell, aiding in maintaining sperm cell integrity. A study conducted at the University of Padua and published in the “Journal Science” states that a diet low in selenium could be a cause of male infertility. The reason why selenium is important for the quality of sperm is due to the fact that  fights the free radicals, so it may also avoid the breakage of chromosome, which is known to cause infertility or failure to conceive and birth defects. In one Scottish study, received either a composite tablet containing selenium and vitamins and minerals or a placebo tablet to be taken daily for a period of 3 months. The sperm quality was recorded before and after the study. Showed  that the motility of sperm cells in the treatment groups had increased by as much as 80 % but when the men stopped taking the tablet, their sperm cell quality was seen to fall again.

Selenium Deficiency Symptoms

When intense selenium deficiency is accompanied by severe overall malnutrition, symptoms can include weakness or pain in the muscles, discoloration of the hair or skin, and whitening of the fingernail beds.

Selenosis Symptoms

High blood levels of selenium can result in a condition called selenosis. Symptoms of selenosis include gastrointestinal upsets, hair loss, garlic breath odor, white blotchy nails, fatigue, irritability, and mild nerve damage. The Institute of Medicine of the National Academy of Sciences has set a tolerable upper intake level for selenium at 400 micrograms per day for adults to prevent the risk of developing selenosis.

Selenium Dosage

The recommended daily intake of selenium is 55 micrograms  per day for adults. For pregnant or breastfeeding women, 60 to 70 mcg are recommended. The safe upper limit for selenium is 400 mcg a day in adults. In studies supporting the use of selenium for prostate cancer prevention, men took 200 mcg daily.

Types of Selenium Supplements

Inorganic forms of selenium are sodium selenite, and sodium selenate. Inorganic forms are not absorbed as organic forms. Selenium yeast and selenomethionine are an organic form of selenium. In one experiment, selenium levels in red blood cells of people receiving selenomethionine increased by 100% after sixteen weeks supplementation. Neither selenite nor selenate produced significant increases under the same conditions.

Selenium Sources in Food

Brazil nuts, Brewer’s yeast, wheat germ, garlic, sunflower seeds, chives, raisins, eggs, whole grains, brown rice, mozzarella cheese, mushrooms, mackerel, halibut, herring, tuna, cod, salmon, redsnapper, swordfish, flounder and shellfish selenium-containing foods. The amount of selenium in food depend on how much selenium was in the soil where the food was grown. Selenium is destroyed when foods are refined or processed.

Vitamin E is a fat-soluble antioxidant that stops the production of  reactive oxygen species (ROS) formed when fat undergoes oxidation. Vitamin E exists in 8 different isomers. Some members of the vitamin E family are called tocopherols (alpha tocopherol, beta tocopherol, gamma tocopherol, and delta tocopherol). Other members of are called tocotrienols  (alpha, beta, gamma, and delta tocotrienol). Alpha-tocopherol is the most active form in humans. Hence, it is the form of vitamin E found in the largest quantities in blood and tissues vitamin E supplements are available in synthetic or natural  forms. The natural forms are usually labeled with the  “d“, synthetic forms are labeled “dl“. Vitamin E supplements are taken as capsules, with a typical dose 400 IU per day. The natural form is more active and better absorbed.

Vitamin E Deficiency

People with fat-malabsorption disorders are more likely to become deficient than people without such disorders. Patients with health problems, such as liver diseases, cystic fibrosis, and Crohn’s disease may need extra vitamin E. Symptoms of vitamin E deficiency;  muscle weakness, vision problems, abnormaleye movements, loss of coordination.

Vitamin E Sources in Food

Wheat germ oil, sunflower seeds, sunflower oil, olive oil, hazelnuts, almonds, eggs, kiwi, mango, spinach,broccoli, tomato, mustard greens, asparagus.

Antioxidant

Antioxidants are molecules which can interact with free radicals and terminate the chain reaction before vital molecules are damaged. Without adequate levels of antioxidants, these free radicals travel throughout the body, damaging cells. Lab and animal research have shown that antioxidants help prevent the free radical damage that is associated with cancer. While alpha tocopherol inhibits free radical production,  gamma tocopherol is required to trap and neutralize existing free radicals. In a test tube study, gamma tocopherol was found to be more effective than alpha tocopherol in protecting against specific types of oxidative damage.

Supporting Immune

Vitamin E  plays a role in your immune system and metabolic processes. Needs vitamin E to help keep the immune system strong against  bacteria and viruses. Is also important in the formation of red blood cells. Vitamin E stimulates the production of NK cells (natural killer cells), those that seek out and destroy germs and cancer cells. A study involving healthy people over age 65 has shown that increasing the daily dose of vitamin E from the recommended dietary allowance (RDA) of 30 mg to 200 mg increased antibody responses to hepatitis B and tetanus after vaccination. A randomized, placebo-controlled trial in nursing home residents reported that daily supplementation with 200 IU of alpha-tocopherol  for one year significantly lowered the risk of contracting upper respiratory tract infections, especially the common cold. Taking 200 IU of vitamin E by oral for more than ten years seems to help prevent death from bladder cancer. In one prospective study, increased levels of plasma gamma-tocopherol were associated with a noticeably extent risk of developing prostate cancer. One study of women in Iowa provides evidence that intakes of vitamin E from foods and supplements could decrease the risk of colon cancer, especially in women.

Heart Disease

This vitamin  supports your vascular health by preventing substances from sticking to blood vessel lining cells and promoting relaxation of your arterial walls. One study of approximately 90,000 nurses found that the incidence of heart disease was 30 to 40 percent lower in those with the highest intakes of vitamin E, primarily from supplements. This study was published in the 1993 New England Journal of Medicine. Among a group of 5,133 Finnish men and women followed for a of 14 years, higher vitamin E intakes from food were associated with decreased mortality from coronary heart disease (CHD). A randomized, placebo -controlled intervention trial in Great Britain found that supplementing heart disease patients with either 400 IU or 800 IU of synthetic alpha-tocopherol  for an of 18 months substantially reduced the occurrence of nonfatal heart attacks by 77 %.

Macular Degeneration

Taking vitamin E by oral in combination with beta-carotene, vitamin C and zinc might slow the worsening of advanced age-related macular degeneration. The study showed that a 400 IU/day intake of vitamin E, taken with vitamin C, beta-carotene and zinc supplementation, slows the progression of advanced age-related macular degeneration by 25 % in individuals at high-risk for the disease. Vitamins C and E may also help treat uveitis.

Infertility

Vitamin E has a protective property on sperm cell and by keeping them from getting damaged, it improves fertility and quality. Several studies have reported positive effects of antioxidants on semen quality. Vitamin E protects against the reactive oxygen species (ROS) mediated damage on spermatozoa. Combined with vitamin C, vitamin E plays role in preventing sperm clumping together, and promoting motility. Vitamin E has been shown to increase the ability of sperm to fertilize an egg in test tubes. Selenium is an essential mineral for normal testicular development, spermatogenesis, and spermatozoa motility and function. “The University of Maryland Medical Center” recommends taking 400IU per day of vitamin E to prevent or treat sexual dysfunction like depressed sex drive that may result  from hormonal imbalance. A study published 2011 in the “International Journal of General Medicine” found semen quality improved and sperm motility improved in infertile men who took 400 IU  of vitamin E and 200 mcg of selenium daily for 3 months.

Menstrual Cramps and Premenstrual Syndrome

400 IU of Vitamin E (least) daily may help relieve the pain of menstrual cramps. Painful menstruation, affects up to 50% of women but usually menstrual pain does not mean a more serious problem. Taking vitamin E for two days before and for three days after bleeding begins seems to decrease pain severity and duration, and reduce menstrual blood loss. Vitamin E may be help for alleviating menstrual cramps and decreasing blood loss during menstruation, according to the “British Journal of Obstetrics and Gynaecology“.  In one study, 100 young women took either 500 IU of vitamin E or placebo for five days . Women who used vitamin E reported less pain than those who took placebo. A cocktail containing vitamin E and essential fatty acids may help reduce symptoms of premenstrual syndrome, Brazilian researchers report in Reproductive Health. The scientists, from the Federal University of Pernambuco, in Brazil, believe the contents of the cocktail make the body less sensitive to prolactin, a hormone blamed for fluid retention and breast tenderness. Too much prolactin or an abnormal response to this hormone may cause premenstrual syndrome symptoms.

Vitamin E Daily Dosage Recommended

Vitamin E  is measured as milligrams (mg) of alpha-tocopherol. It also can be measured as  International Units (IU). 400 to 800 IU equals 268 to 536 mg.  The RDA for vitamin E is just 15 milligrams (about 23 IU) a day. “The National Academy of Sciences” set a Tolerable Upper Intake Level (UL) for vitamin E of 1,000mg (or 1,500 IU of vitamin E in the form of alpha-tocopherol).  This daily limit is intended to apply to all individuals age 19 and older. A study published in the” Proceedings of the National Academy of Sciences” recommends that at least 20 percent of vitamin E supplement should consist of the gamma tocopherol form.

Vitamin E Side Effects

Alpha-tocopherol high amounts of can inhibit platelet aggregation and antagonize vitamin K-dependent clotting factors. Two clinical trials have found an increased risk of hemorrhagic stroke in participants taking Vitamin E (alpha-tocopherol). Nausea and gastric distress have been observed in a few patients taking high dosages (2000-2500 IU/d).  Diarrhea and intestinal cramps have been reported at a dosage of 3200 IU. Stop using this vitamin at least two weeks before a scheduled surgery.

Selenium is an essential mineral required in small amounts. This vital mineral was discovered in 1817 by Swedish chemist, Jons Berzelius. In 1957, Foltz  and Schwartz established selenium as an essential trace element in nutrition for the prevention of disease. The human body selenium content is considered to be  average 12-20 milligrams. Selenium is present in almost every cell in the body. However mostly, is found in the kidneys, liver, spleen, pancreas, thyroid, testes, and the lymph nodes.

Sources of High Selenium

Brewer’s yeast, Brazil nuts, wheat germ, butter, garlic, chives, sunflower seeds, raisins, eggs, whole grains, brown rice, lean meats, cheddar, mozzarella cheese, mustard seeds, mushrooms, halibut, mackerel, herring, smelts, tuna, cod, salmon, redsnapper, swordfish, flounder and shellfish selenium-containing foods. The level of selenium in plants depends on the soil in which they are grown. Selenium can be lost when food is processed or refined.

Selenium Benefits

Requires selenium to create selenoproteins, enzymes important to human health. Selenoproteins are antioxidants that protect cells from free radical damage. Free radicals are by-products of oxidation and can occur during normal metabolism, can also be exposed to free radicals in smoke or other toxic exposures. Selenium is a vital component of the antioxidant enzyme known as glutathione peroxidase. Production of glutathione peroxidase for free radical scavenging depends upon the availability of selenium. (The level of blood selenium is determined by measuring the of this enzyme. Erythrocyte, serum and tissue levels of glutathione peroxidase can be measured to assess selenium rate. Selenium in hair and nails can also be measured). Glutathione peroxidase protects cell membranes from effect from free radicals released from hydrogen peroxide formed during normal metabolism in the cells mitochondria. Selenium and vitamin E have complementary however independent effects as antioxiadants in the protection of cells against the damaging effects of lipid peroxides and free radicals producedduring normal metabolism. Vitamin E and selenium work synergistically. Selenium when combined with vitamin E, it has demonstrated anti-inflammatory effect.

Selenium and Sulforaphane

Sulforaphane and selenium have also been shown to work synergistically protecting the body cells against damage caused by free radicals. Sulforaphane and other isothiocyanates have a chemical structure that makes them antioxidants. That is, although both selenium and sulforaphane have beneficial effects alone, when they are combined it is reported that their cancer fighting properties are increased thirteen fold. When combined, sulforaphane and selenium had a bigger impact on the genes than they did alone. The research in question is published in the journal “Carcinogenesis“.

Immune Response

Selenium, can help build up white blood cells, which boosts the body’s ability to fight illness and infection. Selenium supplementation in individuals who are not overtly selenium deficient appears to stimulate the immune response. Selenium supplementation was found to reduce the viral load in patients infected with human immunodeficiency virus (HIV). Selenium may increase resistance to HIV by enhancing the action of T-cells and modifying their production of cytokines. In a 2007 study conducted by the University of Miami; researchers observed that the selenium group reduces HIV viral load compared to the placebo group. In addition, selenium plays a role in reducing cellular stress and breakdown caused by the HIV virus. Selenium helps to produce antibodies, proteins in the blood and lymph that destroy bacteria, viruses and parasites that attack the body.also, selenium may stimulate the formation of antibodies in response to vaccines.

Anticancer

Often have low levels of selenium in cancer patients. A study published in the “American Journal of Epidemiology” measured serum selenium levels in over 9,000 Finns from 1968 to 1976. The research in question; revealed that those who previously had serum selenium amounts of less than 46 ng/ml were more likely to get lung cancer. Five-year study conducted at the the Cornell University and University of Arizona showed that consumption of 200 micrograms of selenium daily resulted in 63% fewer prostate tumors, 58% fewer colorectal cancers, 46% fewer lung malignancies, and a 39% overall decrease in cancer deaths. Selenomethionine is considered to be the best absorbed and utilized form of selenium. In one study of 1,312 people, those who took 200 mcg of selenium  per day had 2/3 lower risk of developing prostate cancer during the 4.5-year study compared to those who took a placebo. In a 1997 study published in Biomedical and Environmental Sciences, supplements of 200 mcg of selenium a day were shown to lower the risk of  mortality from prostate, colorectal and lung cancers. Researches indicates that the methylated forms of selenium are the active species against tumors, and these methylated selenium compounds are produced at the greatest amounts with excess selenium intakes. A study conducted at “Harvard University“; found that men with high selenium levels have a 65 % lower chance of getting prostate cancer and recommends 159 micrograms of the mineral for the protective effect. Study results published in 2004 in the Journal of the National Cancer Institute found that people with the highest blood levels of selenium had a 34 % lower risk of abnormal cell growth and developing new polyps in the rectum and colon. Anticancer mechanism of selenium; 1-As anti-oxidant, can help protect the body from harmful effects of free radicals. 2- improving immune system function. 3-increasing the levels of selenium metabolites that inhibit tumor cell growth. 4-Affecting the metabolism of carcinogens. 5- Selenium has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis.

Thyroid

Selenium is a critical mineral for maintaining healthy function of the thyroid gland. Is a necessary component of three enzymes that contribute to thyroid hormone production and your thyroid contains more selenium than any other tissue in your body. (Selenium is needed in the conversion of the thyroid hormone T4 into its active version, T3).  In order for the thyroid to produce the most active form of its hormone, selenium is not only essential, also helps regulate the amount of hormone that is produced. Selenium and iodine work together to convert the inactive hormone T4 into active T3 to circulate properly in your bloodstream and signal different cellular functions. In addition, selenium may have the ability to suppress anti-thyroid antibodies for persons who suffer from thyroid inflammation or thyroiditis.

Male Fertility

Selenium increases fertility in men by enhancing sperm production and sperm movement. Blood selenium amounts have been found to be lower in men with low sperm counts. A young and healthy man produces more than four million sperm per hour in each testicle. Selenium acts to help prevent oxidation of the sperm cell, aiding in maintaining sperm cell integrity. Research has shown that selenium improves the health of Leydig cells inside testes. This has the beneficial effect of improving sperm quality. In one Scottish study; (96 men), received either a composite tablet containing selenium and vitamins and minerals  or a placebo tablet to be taken daily for a period of three months. The sperm quality was recorded before and after the study. Showed  that the motility of sperm cells in the treatment groups had increased by as much as 80 % but when the men stopped taking the tablet, their sperm cell quality was seen to fall again. (To produce improvement in sperm quality, a daily intake of 130 mcg  per day is required.) In another study, 500 infertile men took 200 micrograms of selenium per day, 600 mg of NAC (N-acetyl-cysteine) per day, these two nutrients combined or a placebo. After 26 weeks, men who had taken NAC and selenium together had more sperm with normal structure and form, more balanced levels of a group of hormones that regulate and control the number of sperm, more concentrated sperm counts and better sperm movement. (“Journal of Urology,” date of publication 2008)

Selenium Supplements

•Selenomethionine

•Selenium yeast

•Selenium-amino acid chelates

•Sodium selenite and sodium selenate

Selenium yeast and selenomethionine are an organic form of selenium. Inorganic forms of selenium are sodium selenite, and sodium selenate. Inorganic forms are not absorbed as organic forms. Selenite has about a 50 % absorption level. Selenate is almost completely absorbed. Selenate is almost completely absorbed. But, a significant amount is excreted in the urine before it can be used by the body’s protein. In one study, selenium levels in red blood cells of people receiving selenomethionine increased by 100% after 16 weeks supplementation. Neither selenate nor selenite produced significant increases under the same conditions.

Maximum Daily Dose of Selenium

The RDA for Selenium is 55-70 micrograms (mcg), and recommendations include 100-200 micrograms. Dosage should not exceed 400 micrograms per day. The doses used in experimental studies; To strengthen the immune system 100 mcg. Infection 100 mcg. To prevent cancer; 200 mcg, colon cancer 200 mcg. HIV 400 mcg.

Selenium Toxicity Symptoms

Nausea, vomiting, diarrhea, nail changes, hair loss, skin lesions, facial flushing, garlic breath, muscle cramps, joint pain and loss of energy. Selenium supplements should not be taken with anticoagulant medications or medications that slow the blood-clotting process. This mineral is also;  may interact with other medicines, such as, chemotherapy drugs, corticosteroids, statin drugs, birth control pills and antacids.

Mistletoe is a parasitic plant that grows on oak or elm trees. Iscador is Weleda’s proprietary cancer treatment formulation derived directly from the mistletoe plant. In 1920, Rudolf Steiner, started promoting iscador as a cancer treatment. Weleda co-founder Dr. Rudolf Steiner first suggested it specifically for cancer patients in the early 20th century, and with increasing successes in treatment since that time, its use has become widespread (Other brands of mistletoe; Isorel, Eurixor and Helixor). For more than 80 years, an aqueous extract of Viscum album, named Iscador, has been used as an anticancer drug. Iscador is licensed for mono and adjuvant  anti-cancer therapy in Switzerland, the European Union, and several countries around the world.

Iscador Mistletoe Extract

Iscador is ‘made from fermented extracts of European mistletoe, some forms of which are combined with small amounts of metals to produce certain desired, anticancer effects’. In Germany, a variety of Iscador preparations are available: M (mali = apple tree), P (pini = pine),  U (ulmi = elm) and Qu (quercus = oak) ; in Switzerland, a (abietis = spruce) is also available.

Iscador Effectiveness

Iscador have been recommended for use in helping treat cancers of the breast, cervix, stomach, colon and lung, as well as lymphoma and leukemia and sarcoma. Iscador is thought to work against cancer by shrinking tumors and attacking malignant cells. According to studies; have found that iscador may increase the amount of white blood cells, as well as increase their activity, strengthening the immune system. Proponents says mistletoe extract injected directly into or near a tumor can slow and possibly reverse the growth of cancer cells, even in advanced cases of cancer.

Opinions

According to Weleda, 50 % of Germans with cancer are given mistletoe as treatment. In a research conducted by the “Institute for Preventive Medicine in Heidelberg“, people taking Iscador have a better chance of cancer survival than those who do not take it by up to 40 %. German Commission E, has approved mistletoe as a therapy to treat symptoms of malignant tumors. Research in 2009 by the “German Institute of Immunology and Experimental Oncology” has shown  that misletoe extract injected into the body can improve cancer survival times. Adjuvant treatment with iscador can increase the tolerability of conventional cancer treatment, improve patient quality of life, and lengthen tumor free survival, Dr. Paul Bock said.

Mechanism of Action of Mistletoe

Mistletoe contains a cytotoxic lectin, viscumin. It also contains a number of cytotoxic proteins and polypetides. Polypeptides, including lectins and viscotoxins, are thought responsible for immune stimulant and tumor inhibition activities. For this reason, mistletoe has been classified as a type of biological response modifier. Also, extracts of mistletoe have  been shown in the laboratory to prevent the growth of new blood vessels needed for tumors to grow.

What Does Iscador?

• Immunomodulatory effect

• Inhibition of malignant growth

• Reducing the risk of recurrences and metastase

• Reducing adverse effects from chemotherapy and radiation therapy (Protect the DNA in white blood cells in the lab, including cells that have been exposed to DNA-damaging chemotherapy drugs)

• Improvement in quality of life

• Prolongation of life

• An injectable form of mistletoe lectins was found to reduce the frequency and intensity of clinical signs and symptoms in  people with hepatitis C.

How to Apply Treatment?

Iscador is given by subcutaneous injection near or directly into the tumor. It sometimes is injected directly into the tumor particularly on the liver, esophagus and cervix. Also be taken orally in tumors of the brain and spinal cord. As daily therapy progresses, more concentrated iscador extractions are administered. Iscador injections promoted to prevent cancer may involve three to seven injections a week over several months to several years.

Iscador Side Effects

Side effects can include redness at the injection site, headaches, fever and chills. In rare cases allergic symptoms including anaphylactic reactions have been reported. According to some research;  mistletoe injections should not be administered during the first days of the menstrual period. Seizure and death have been reported. A few cases of severe allergic reactions, including anaphylactic shock, have been reported.

The main task of magnesium is enzyme activation. Is required to make more than 300 different enzymes and to send messages along the nerves. The cell mitochondria require magnesium in order to synthesize adenosine triphosphate, the all-important molecule that provides energy for metabolic functions. Other proteins, like those required to produce  RNA and DNA , are also magnesium-dependent. The metabolism of fats and carbohydrates to produce energy requires numerous magnesium-dependent chemical reactions. This mineral is often called the anti-stress mineral because it has a calming effect when taken. Is important for normal heartbeat and nerve transmission. Magnesium is required for the active transport of ions like  calcium and potassium across cell membranes. Therefore, magnesium affects the conduction of nerve impulses, muscle contraction, and normal heart rhythm. Magnesium helps signal muscles to contract and relax. Helps maintain normal levels of calcium, potassium, phosphorus, adrenaline and insulin, and keeps the bones strong and the heart healthy.

The human body contains about 25 grams of magnesium. Approximately 50 percent of total magnesium is found in bone. The other half is predominantly found in the cells of body tissues and organs. Only 1 percent of magnesium is found in blood. This magnesium concentration must be kept at a constant level to keep your body functioning properly. The normal blood levels for magnesium ranges from 1.5  to 2.5 mEq/L. The RDA for magnesium is about 310 mg per day for women and 420 mg per day for men.

Causes of Magnesium Deficiency

Several gastrointestinal diseases, pancreatitis, diabetes, hyperthyroidism and kidney disease can lead to magnesium deficiency. Some drugs may result in magnesium, deficiency including  diuretics, antibiotics, and medications used to treat cancer. Excessive salt, coffee, or alcohol, as well as heavy menstrual periods, over sweating, and prolonged stress can also lower magnesium levels.

Symptoms of Magnesium Deficiency

Insomnia, weakness, loss of appetite, irritability, anxiety, irregular heartbeat, dizziness, low blood pressure, shortness of breath, nail growth, muscle spasm, restless leg syndrome and poor coordination. Important magnesium deficiency can result in low levels of calcium in the blood.

Food with Magnesium

High Magnesium Foods List; Green leafy vegetables, whole grains, legumes, almonds, squash seeds, pine nuts, Brazil nuts, cashews, wheat germ, sunflower seeds, sesame seeds, flax seeds, raisins, molasses, oysters, halibut, dairy products, tofu, brown rice, lima beans, split peas, lentils, black-eyed peas, bean sprouts, wheat and oat bran, spinach, lettuce, beet greens, broccoli. Other good dietary sources of this mineral; oatmeal and oat flour, soybean flour, bananas, avocados, figs, baked potatoes with skin, cocoa powder, chocolate, kelp. Because magnesium is part of chlorophyll, the green pigment in plants, green leafy vegetables are rich in this mineral. Unrefined grains also have high magnesium content. Nearly 85% of the magnesium is lost when whole grains are refined to white flour. Harder water usually has a higher concentration of magnesium salts. Supplemental forms of magnesium are available as magnesium gluconate, magnesium oxide, magnesium chloride, and magnesium citrate salts, as well as a number of amino acid chelates, including magnesium aspartate.

Magnesium Research

Scientific researchs indicate that supplementing with magnesium may help prevent asthma, migraine, osteoporosis, high blood pressure and cardiovascular disease.

Asthma

Asthma is a disease where the bronchial passages go into spasm and interfere with normal breathing. Magnesium sulfate is used as a therapy for asthma. A study from Brown University showed pronounced improvement in children with asthma who were treated with intravenous magnesium. Effects of magnesium include relaxing the airways, acting as a bronchodilator for asthma.

Migraine

Individuals who suffer from recurrent migraine headaches have lower intracellular magnesium levels than patients who do not experience migraines. Magnesium was found to reduce the frequency, intensity and length of migraines or headaches in many studies. 200 mg to 600 mg daily is  used to help prevent migraine headaches. Magnesium and Migraines

Preeclampsia-Eclampsia

Magnesium, given in the hospital intravenously, is the therapy of effective to prevent or treat seizures associated with eclampsia or to prevent complications from preeclampsia. Preeclampsia-eclampsia is a disease that is unique to pregnancy and may occur anytime after 20 weeks of pregnancy through 6 weeks following birth.

Kidney Stones

When combined with vitamin B6 (pyridoxine) it helps to reduce and dissolve calcium phosphate stones. Jonathan Wright, recommends  100 milligrams of vitamin B6, and 300 milligrams of magnesium citrate, daily.

Cardiovascular Diseases

Intravenous magnesium application has been shown to be effective in reducing mortality in thombolysis-ineligible patients with acute myocardial infarction. Magnesium helps maintain a normal heart rhythm and is sometimes given intravenously to reduce the chance of atrial fibrillation and cardiac arrhythmia. Intravenous magnesium, when given as soon as possible after a heart attack, decreases death rate.

High Blood Pressure

High blood pressure is one of the major vascular disorders that magnesium can help. High blood pressure,defined as having a systolic and diastolic blood pressure  greater than 140 and 90 mmHg, is a major risk factor for cardiovascular disease. Magnesium is an essential micronutrient in maintaining suppleness in the walls of blood vessels. In twelve randomized controlled trials, patients receiving magnesium supplements did not have a significantly reduction in systolic blood pressure. However they had a significant reduction in their diastolic blood pressure.

Diabetes

Inadequate blood levels of magnesium may prohibit the release of insulin from the pancreas. Therefore, regulation of blood glucose levels is disrupted and blood glucose rises abnormally. Magnesium supplementation may help diabetics to maintain adequate magnesium levels as well as improve glucose tolerance. Studies have shown that for every 100 mg of magnesium, the risks of diabetes is reduced by 15 percent. Magnesium supplementation may help overweight individuals who have become insulin resistant improve their condition and avoid type 2 diabetes, according to a  study from German researchers.

Osteoporosis

Osteoporosis, a disease characterized by weak bones. Magnesium, along with calcium and Vitamin D can prevent the development of osteoporosis. Since magnesium works closely with calcium, it is necessary  to have an appropriate level of both minerals in order for them to be effective. If you take 1000 mg of calcium, you should also take 500 mg of magnesium. This is to be taken in two divided doses with Vitamin D 400 IU with each Calcium dose, this helps absorption of both magnesium and calcium. Thirty-one woman suffering from osteoporosis with documented deficiency in magnesium were given a magnesium supplement. After 1 year 71 % of the  patients had increased bone density by up to 8 percent, and the improvement remained unchanged for 2 years.

Sleep Problems

Magnesium works in combination with the calcium to help our muscles relax and in this way allows us to have a better night’s sleep. Calcium helps the brain use the amino acid tryptophan to manufacture the sleep-inducing substance melatonin. In addition, magnesium suppresses the release of catecholamines, which stimulate activity in the sympathetic nerves. Studies show a lack of magnesium can alter electrical activity in the brain, causing agitated sleep and frequent awakenings. A article published  in the Journal of Orthomolecular Medicine confirms the effects of magnesium deficiency on insomnia. Important to note that a balanced ratio of magnesium and calcium is important to overall health, and these two minerals should be taken together for best effects.

Attention Deficit Hyperactivity Disorder (ADHD)

Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood disorders. The exact cause is unknown. However inherited genetic factors are likely responsible. In addition to genetics, scientists are looking at possible environmental factors, and are studying how brain injuries, nutrition, and the social environment might contribute to ADHD. Children with attention deficit hyperactivity disorder may have three basic problems, they can’t pay attention, they are hyperactive, they act on impulse. Children with attention deficit hyperactivity disorder have low magnesium levels than the average child.In one trial, 50 ADHD (attention deficit hyperactivity disorder) children with low magnesium were given 200 mg of magnesium a day for nearly 6 months. When compared with 25 other magnesium-deficient ADHD children, those that were given magnesium supplementation appeared to experience a decrease in hyperactive behavior. In one  study of 75 magnesium-deficient children with attention deficit hyperactivity disorder, those who received magnesium supplements showed an improvement in behavior compared to those who did not receive the supplements. Russian doctors used a combination of  magnesium and  vitamin B6 to treat children aged from 6 to 12 with attention deficit hyperactivity disorder. Vitamin B6 in the appropriate dose helps determine how much magnesium absorbs into cells.